At Neurokin, we offer skin biopsy testing for small fiber neuropathy (SFN) and dysautonomia—conditions that affect the body’s small nerve fibers and autonomic nervous system. Our minimally invasive biopsy procedure helps detect nerve damage early, enabling timely treatment to alleviate symptoms and prevent further progression.
Small fiber neuropathy (SFN) is a type of peripheral neuropathy that primarily impacts small sensory nerves responsible for pain and temperature regulation
Small fiber neuropathy (SFN) is a type of peripheral neuropathy that primarily impacts small sensory nerves responsible for pain and temperature regulation. Left untreated, SFN can progressively impair sensory function, reducing the quality of life. Symptoms of SFN can include:
Dysautonomia refers to a group of conditions that affect the autonomic nervous system (ANS), responsible for regulating involuntary bodily functions such as heart rate, blood pressure, digestion, and sweating. Since these symptoms often overlap with other conditions, a skin biopsy is a critical diagnostic tool for confirming nerve damage associated with SFN and autonomic dysfunction. Symptoms may include:
A skin biopsy is a minimally invasive procedure used to evaluate nerve fiber density in small skin samples. These samples are examined in a laboratory to detect any damage or loss of small nerve fibers.
Highly Accurate
Skin biopsy is the gold standard for diagnosing small fiber neuropathy.
Minimally Invasive
Only a small sample of skin is removed using local anesthesia, leaving minimal scarring.
Precise Results
The biopsy reveals the density of small nerve fibers, helping differentiate SFN from other forms of neuropathy and autonomic disorders.
Initial Consultation
Our specialists will review your medical history and symptoms, conducting a clinical evaluation to determine whether skin biopsy testing is appropriate.
Skin Biopsy Procedure
The biopsy involves removing small skin samples (3-5mm) from targeted areas, typically from the thigh, calf, or forearm. The procedure is quick and minimally painful, requiring only local anesthesia.
Lab Analysis
The samples are sent to a specialized laboratory, where experts measure nerve fiber density and check for any signs of degeneration or damage.
Comprehensive Results and Follow-Up
Once the lab results are in, our team will discuss the findings with you, helping you understand the diagnosis and treatment options. We’ll also provide personalized recommendations for managing your symptoms.
We take a multidisciplinary approach to treatment, offering solutions that address the root cause of your symptoms. We work closely with you to develop an individualized care plan that improves your comfort, quality of life, and long-term outcomes. Treatment plans may include:
Medications
Medications to manage pain and autonomic symptoms
Physical therapy
Physical therapy to improve mobility and strength
Lifestyle modifications
Lifestyle modifications such as hydration and dietary changes for autonomic stability
Specialized therapies
Specialized therapies, such as IV fluids or immunotherapy, if the underlying cause is autoimmune
We specialize in diagnosing small fiber neuropathy (SFN) and Dysautonomia with precise, data-driven testing. Our clinicians are experienced in nerve-related disorders, ensuring accurate diagnoses and personalized care for long-term results.
Our skin biopsy procedure is quick and minimally invasive, performed in a comfortable clinic setting with local anesthesia. We offer flexible appointment options to fit your schedule and ensure timely diagnosis with fast, detailed results.
Neurokin goes beyond diagnosis by creating individualized care plans tailored to each patient. With access to multidisciplinary treatment options such as physical therapy, medication, and lifestyle support, we help you manage symptoms effectively and improve your quality of life.
How long does the biopsy procedure take?
The biopsy procedure takes approximately 15-30 minutes and is performed in our clinic under local anesthesia.
Will the biopsy be painful?
The procedure is minimally painful, as only a small area of skin is numbed with local anesthesia. Patients typically report mild discomfort afterward, with the site healing within a few days.
How soon will I get the biopsy results?
Lab results are usually available within 2-3 weeks. Once we receive the results, we’ll contact you to review the findings and discuss your next steps.
Are there any risks associated with the biopsy?
Skin biopsies are generally safe with minimal risks. In rare cases, you may experience mild bleeding, infection, or scarring at the biopsy site, but these complications are uncommon.
Is skin biopsy covered by insurance?
Many insurance providers cover skin biopsies for neuropathy and autonomic testing. We recommend checking with your insurance company for specific coverage details.
What happens if the biopsy shows signs of nerve damage?
If nerve damage is confirmed, our team will work with you to develop a personalized treatment plan. This may include medications, physical therapy, or other interventions to manage your symptoms and improve your quality of life.